Relapsing Aspergillus bronchitis in a double lung transplant patient, successfully treated with a new oral antimycotic agent.

were unremarkable except for mild hepatosplenomegaly. Labo¬ ratory tests revealed a serum hemoglobin level of 11.4 g/dL, WBC count of 3.4X109/L, and platelet count of 79X109/L. Results of liver and renal function tests and urinalysis were within normal limits. Findings on chest radiograph were normal. Thirty-six hours later, the patient had high-grade fever (40.5°C), tachypnea, dyspnea, and acute pain in the anterior chest wall. Blood gas analysis (fraction of inspired oxygen, 0.21) revealed a pH of 7.5, Pa02 of 64.6 mm Hg, PaC02 of 29.1 mm Hg, and HCOs of 23.1 mmol/L. The chest radiograph showed bilateral interstitial infiltrates. Two separate peripheral blood